Epidermolysis Bullosa Acquired- Symptoms, Causes, Treatment
What is Epidermolysis Bullosa Acquired?
Epidermolysis bullosa acquire (EBA) is an antibody-mediated autoimmune blistering defect. Epidermolysis bullosa is a collection of 25 hereditary and non-hereditary stages which are responsible for skin and mucosal patches. These patches occurs on the hands & feet but also they may occur on any part of the body and thae scars remain as it is. Commanly EBA affect to the areas that easily get injured like hands, feet, knees, elbows etc. EBA is also related to mellitus, tuberculosis, or colitis. This is classified in three types that are simplex, junctional, and dystrophic epidermolysis bullosa. In animals, it found only in dogs.
Causes of Epidermolysis Bullosa Acquired
- Any type of skin inflamation, open wounds and sores infections are the main causes of EBA.
- Epidermolysis bullosa acquired may also inherited from parents to child.
- Medication side effect and periodontal disease may be the causes of EBA.
What are the symptoms of Epidermolysis Bullosa Acquired?
- In EBA skin and mucus membrane get affected effectively is the main symptom.
- Generation of spots take place on the various parts of body like hands, knees, feet, elbows, ankles and the scars remain as it is on the body.
- Possibility of formation of erythema, urticarial plaques, and generalized pruritus in some patients.
- Oral blistering occurs in some cases.
- Epidermolysis bullosa acquire associates with other diseases like anaemia, recurrent infections, nails anomalies, abnormal corneal structure, hearing loss and stillbirth or neonatal death.
- Difficulties for feeding in infancy and intrauterine growth retardation take place.
Epidermolysis Bullosa Acquired Treatment
- Preventing trauma and friction is the first step of treatment and also controlling infections.
- Corticosteroid treatment which include calcium and vitamin D supplements is essential for EBA patient.
- In some cases use of immunosuppressive and anti-inflammatory agents take place.
- Drugs like deltasone, azathioprine, oxsoralen, avlosulfon, colchicine also useful to stop the growth of autoantibodies and to reduce the responses of autoimmune.
- Patient must have to take precaution in diabetes during epidermolysis bullosa acquire.
- Some patients make use of petroleum jelly, gauze, and ointments for the treatment of patches.
- Plastic surgery is also useful to releve skin defects and to restore functions of fingers & toes.
- Avoid hard food or food with high acid.
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