Calciphylaxis- Symptoms, Causes, Treatment and Home Remedies

What is Calciphylaxis?

Calciphylaxis (cal-ci-phy-lax-is) is a dangerous disease due to deposition of calcium form blood vessels into the skin (process known as calcification) which can lead to hypersensitivity. It results in painful skin ulcers, some skin infections and organ failures, itching and burning sensation, bleeding from the affected area, some purple or red colored lesions on trunks, abdomen, buttocks or thighs. It is most commonly seen in the people who are at the last stage of their kidney disease. It can also be rarely seen in the people suffering from breast cancer, rheumatoid arthritis, or liver cirrhosis. It can be rare but serious one. Females get affected more than males.

Calciphylaxis is also referred as uremic gangrene syndrome, uremic necrosis, uremic small-artery disease with medial calcification and intimal hyperplasia, calcific uremic arteriolopathy, obliterative calcific-thrombotic arteriolopathy, calcifying panniculitis.

Causes of Calciphylaxis

What are the symptoms of Calciphylaxis?

Calciphylaxis Treatment.

Main treatment is discontinuation of corticosteroids, phosphate, iron, calcium and vitamin D products in the diet.
Dialysis is prescribed to the patients who are already under dialysis.
Hyperbaric oxygen and cimetidine can show considerable effect to treat calciphylaxis.
Tissue plasmnogen activator, blood thinning medications may also be used in the treatment in some cases.
Anticoagulation therapy is used to treat the patients with protein C and protein S deficiencies.
Antibiotics and pain relief medications are the other sources of treatment.
Surgery is necessary in some cases to remove all or part of the parathyroid glands, and dead or contaminated tissue, to prevent infection.

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